Endocrine Abstracts

Background: Despite the preserved left ventricular(LV) ejection fraction, patients with acromegaly are characterized by subclinical systolic dysfunction, i.e. abnormal global longitudinal strain(GLS) assessed by speckle-tracking echocardiography(STE). The effect of acromegaly treatment on LV systolic function assesed by STE has not been evaluated so far.Patients and methods: Thirty two naïve acromegaly patients with no detectable heart disease were ...

Introduction: Cardiac disease called acromegalic cardiomyopathy may be present in patients with acromegaly at diagnosis, however most echocardiographic studies showed that systolic function, measured by ejection fraction (EF), in these patients is normal. Speckle tracking echocardiography (STE) is a novel method that allows for the study of global longitudinal strain (GLS), a marker of early and subclinical left ventricular (LV) systolic dysfunction. Some studies show subclini...